抄読会

17th ( Dec. 14. 2022. 18:15 - ) Kenta Nagahori

MAGE cancer-testis antigens protect the mammalian germline under environmental stress. 

Fon Tacer K, Montoya MC, Oatley MJ, Lord T, Oatley JM, Klein J, Ravichandran R, Tillman H, Kim M, Connelly JP, Pruett-Miller SM, Bookout AL, Binshtock E, Kamiński MM, Potts PR.

Sci Adv. 2019 May 29;5(5):eaav4832. 

16th ( Nov. 30. 2022. 18:15 - ) Naoyuki Hatayama

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

Chouchani ET, Pell VR, Gaude E, Aksentijević D, Sundier SY, Robb EL, Logan A, Nadtochiy SM, Ord ENJ, Smith AC, Eyassu F, Shirley R, Hu CH, Dare AJ, James AM, Rogatti S, Hartley RC, Eaton S, Costa ASH, Brookes PS, Davidson SM, Duchen MR, Saeb-Parsy K, Shattock MJ, Robinson AJ, Work LM, Frezza C, Krieg T, Murphy MP.

Nature. 2014 Nov 20;515(7527):431-435. 

15th ( Nov. 16. 2022. 18:15 - ) Eri Nanizawa

A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice.

Miszta A, Kopec AK, Pant A, Holle LA, Byrnes JR, Lawrence DA, Hansen KC, Flick MJ, Luyendyk JP, de Laat B, Wolberg AS.

Blood. 2020 May 7;135(19):1704-1717. 

14th (Oct. 26. 2022. 18:15 - )  Toshikatsu Ikeda

Ovarian cancer cell fate regulation by the dynamics between saturated and unsaturated fatty acids.

Zhao G, Tan Y, Cardenas H, Vayngart D, Wang Y, Huang H, Keathley R, Wei JJ, Ferreira CR, Orsulic S, Cheng JX, Matei D.

Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2203480119. 

13th (Oct. 12. 2022. 18:15 - )  Hoshizora Ichinose

A bioinspired carbon monoxide delivery system prevents acute kidney injury and the progression to chronic kidney disease.

Nagasaki T, Maeda H, Taguchi K, Yanagisawa H, Nishida K, Kobayashi K, Wada N, Noguchi I, Murata R, Sakai H, Kitagishi H, Saruwatari J, Watanabe H, Otagiri M, Maruyama T.

Redox Biol. 2022 Aug;54:102371.

12th (Sep. 28. 2022. 18:15 - )  Yuki Katoh

Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity.

He Y, Fu L, Li Y, Wang W, Gong M, Zhang J, Dong X, Huang J, Wang Q, Mackay CR, Fu YX, Chen Y, Guo X.

Cell Metab. 2021 May 4;33(5):988-1000.

11th (Sep. 14. 2022. 18:00 - )  Tomonori Harada

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.

Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MM, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K, Murphy MP.

Nat Metab. 2019 Sep 30;1:966-974. 

10th (Aug. 31. 2022. 18:00 - )  Toshihiro Sugi

Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.

Luu M, Riester Z, Baldrich A, Reichardt N, Yuille S, Busetti A, Klein M, Wempe A, Leister H, Raifer H, Picard F, Muhammad K, Ohl K, Romero R, Fischer F, Bauer CA, Huber M, Gress TM, Lauth M, Danhof S, Bopp T, Nerreter T, Mulder IE, Steinhoff U, Hudecek M, Visekruna A.

Nat Commun. 2021 Jul 1;12(1):4077. 

9th (Aug. 17. 2022. 18:00 - )  Daichi Seta

Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the anti-tumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody.

Katoh Y, Yaguchi T, Kubo A, Iwata T, Morii K, Kato D, Ohta S, Satomi R, Yamamoto Y, Oyamada Y, Ouchi K, Takahashi S, Ishioka C, Matoba R, Suematsu M, Kawakami Y.

J Immunother Cancer. 2022 Jul;10(7):e004616.

8th (Aug. 3. 2022. 18:00 - )  Naoyuki Hatayama

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.

Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.

Cancer Cell. 2018 Mar 12;33(3):355-367.

7th ( Jul. 20. 2022. 18:00 - )  Kenta Nagahori

Comprehensive functional characterization of cancer–testis antigens defines obligate participation in multiple hallmarks of cancer.

Maxfield KE, Taus PJ, Corcoran K, Wooten J, Macion J, Zhou Y, Borromeo M, Kollipara RK, Yan J, Xie Y, Xie XJ, Whitehurst AW.

Nat Commun. 2015 Nov 16;6:8840. 

6th ( Jul. 6. 2022. 18:00 - )  Shun Otsuka

Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion.

Wu J, Weisshaar N, Hotz-Wagenblatt A, Madi A, Ma S, Mieg A, Hering M, Mohr K, Schlimbach T, Borgers H, Cui G.

Sci Adv. 2020 Jun 12;6(24):eaba3458.

5th ( Jun. 22. 2022. 18:00 - )  Eri Nanizawa

Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol.

Anegawa D, Sugiura Y, Matsuoka Y, Sone M, Shichiri M, Otsuka R, Ishida N, Yamada KI, Suematsu M, Miura M, Yamaguchi Y.

Commun Biol. 2021 Jun 25;4(1):796. 

4th ( Jun. 8. 2022. 18:00 - )  Toshikatsu Ikeda

Endoplasmic Reticulum Stress Contributes to Mitochondrial Exhaustion of CD8+ T cells.

Hurst KE, Lawrence KA, Essman MT, Walton ZJ, Leddy LR, Thaxton JE.

Cancer Immunol Res. 2019 Mar;7(3):476-486. 

3rd ( May. 25. 2022. 18:00 - )  Hoshizora Ichinose

SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis

Zhu T, Wang Z, Zou T, Xu L, Zhang S, Chen Y, Chen C, Zhang W, Wang S, Ding Q, Xu G.

Front Pharmacol. 2021 Nov 1;12:769647. 

2nd ( May. 11. 2022. 18:00 - )  Masaaki Yoshikawa

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery.

Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi Y, Kondo T, Sakai R, Matsuo K, Nakayama T, Yoshie O, Nakatsukasa H, Chikuma S, Shichita T, Yoshimura A.

Nature. 2019 Jan;565(7738):246-250. 

1st ( April. 20. 2022. 18:00 - )  Yuki Katoh

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.

Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM.

Nature. 2019 Feb;566(7744):403-406. 

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